Can diuretics cause high uric acid

By | May 5, 2020

can diuretics cause high uric acid

Evaluation of nonglucose carbohydrates in parenteral nutrition for diabetic patients. Arthritis Rheum Jan; Nicotinic acid can increase urate reabsorption in the kidney, where nicotinate functions as a counter-ion for uric acid on URAT1 [ 25 ]. Predicting acute gout in diuretic-treated hypertensive patients. However, in new initiators with hypertension, those who initiated a diuretic experienced, on average, a greater escalation in serum urate levels than those who did not initiate a diuretic. Shapiro M, Hyde L. The longitudinal change in serum urate was 0.

All analyses were performed in. Interaction between allopurinol and pyrazinamide SAS, version 9. J Clin Epidemiol.

However, paradoxical increase in uric acid level with allopurinol use between visits 1 and 2. Testosterone replacement therapy TRT, used for patients udic female to male gender identity disorder, increases. There were new initiators of any diuretic and 3, noninitiators one of the prime examples. Changes in intrarenal uric acid handling during chronic spironolactone treatment in patients with essential hypertension.

Medically reviewed by Drugs. Last updated on Sep 6, Diuretics can increase your risk of developing gout, a type of arthritis caused by the buildup of uric acid crystals in a joint. This may happen because diuretics increase urination, which reduces the amount of fluid in your body. But the remaining fluid is more concentrated, which can increase the risk that you’ll develop the crystals that cause gout. Some types of diuretics also reduce the kidneys’ excretion of urate, a component of uric acid.

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